On my previous maxed out 2013 iMac and now on my iMac Pro 10-core, I never sense a problem. I always upsample stuff that is 48k or lower to 96k before working so every day I am either at 96k, or 88.2k, and every few months, 192k.
Yes, every day I use WaveLab at 96k and I have two answers for you.
